Needle in Flow Path HPLC Ultra-high Performance High Pressure Liquid Chromatography Machine for Pharmaceutical Industry
Description of High Performance Liquid Chromatography Instrument
High performance liquid chromatography (HPLC) is widely used in analyticalchemistry and biochemistry to separate,identify, and quantify compounds.Fordecades, it has been the method of choice in drug discovery and developmentboth in the pharmaceutical and biopharmaceutical industries and also inacademia. With the advent of ultra-high performance liquid chromatograph(UHPLC) a few years ago, the science of liquid chromatography (LC) has come toa new era. UHPLC provides the separation science with high speed,highresolution, high sensitivity, and short runtime.The ultra-high performance of liquidchromatography is achieved either by ultra-high pressure liquid chromatographicinstrumentation which couples with sub-2 um particle column packing or byconventional high performance liquid chromatography which capitalizes on core-shell (or fused-core) particle column packing. Ultra-highpressure liquidchromatographic system can withstand extremely high pressures,up to 1, 00obars,which a sub-2 um particle column generates.On the other hand, a core-shell particle-packing column usually produces column back pressure up to 400bars.
Technical Datd of High Performance Liquid Chromatography Instrument
| Needle in Flow Path HPLC Ultra-high Performance High Pressure Liquid Chromatography Machine for Pharmaceutical Industry |
| Work Power |
220V, 50HZ
|
| Ambient Temperature |
10-~40°C |
| Relative Humidity |
20-85% |
| System Indicators |
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| Qualitative Repeatiblity |
RSD ≤0.1% |
| Quantitative Repeatability |
RSD ≤0.3% |
| High Pressure Constant Current Pump |
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| Pump Drive Mode |
Linear Motor Pump |
| Gradient Mode |
Binary (4-way solvent) |
| Flow Setting Range |
0.0001~2ml/min |
| Flow Setting Increment |
0.001ml/min |
| Max Operating Pressure |
150MPa |
| Flow Setting Error |
±1.1% |
| Flow Stability |
≤0.09% RSD |
| Gradient Stability |
≤0.02% RSD |
| Column Oven |
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| Temperature Setting Range |
20~90°C |
| Temperature Stability |
± 0.3°C/h |
| Error of Temperature Setting Value |
± 0.5°C |
| Autosampler |
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| Maximum Withstand Pressure |
150MPa |
| Injection Volumn Range |
0.1~10ul |
| Injection Volume Error |
± 0.2ul (Injection Volume 10ul) |
| Injection Repeatability |
＜ 0.3% RSD |
| Linearity |
R≥0.999 |
| Cross-contamination |
< 0.001% |
| Number of Smples |
96 Vials (2*48, 2ml) |
| Temperature Seting Range |
4~40 °C |
| Temperature Stability |
± 1°C |
| Sampling Speed |
15s |
| Ultra-efficient DAD Detector |
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| Baseline Noise |
≤10-6 AU |
| Baseline Drift |
≤0.9x10-3 AU/h |
| Minimum Test Concentration |
2×10-9g/ml (naphthalene/methanol)
|
| Wavelength Range |
190~800nm |
| Wavelength Indication Error |
≤ ±1nm |
| Wavelength Repeatability |
≤ ± 0.1nm |
| Linear |
2.0 AU |
| Sampling Rate |
Up to 100Hz |
| Number of Arrays |
1024 |
| Light Source |
Deuterium (D2) Lamp |
Performance of High Performance Liquid Chromatography Instrument
1. High-precision ultra-high-pressure infusion unit
2. Low system diffusion volume and optimized flow path
3. Needle-in-flow autosampler with ultra-low injection cycle time
4. Extremely low cross-contamination
5. Active preheat function, fast warming rate
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HPLC High Pressure Liquid Chromatography Machine For Pharmaceutical Industry Images
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